Polynucleotides
Polynucleotide treatment is an advanced regenerative injectable designed to repair and rejuvenate the skin from within. Using naturally derived DNA molecules, it stimulates collagen and elastin production, improves hydration, and enhances skin texture for a firmer, more youthful appearance — without adding volume or altering facial shape.
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Polynucleotides
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About Polynucleotide Treatment
Polynucleotides are bio-stimulating molecules derived from purified DNA fragments. When injected into the skin, they trigger the body’s natural repair response, encouraging new collagen and elastin production. This helps improve firmness, elasticity, and hydration, leaving skin smoother and more radiant.
This treatment is ideal for those experiencing dullness, fine lines, or loss of elasticity — and can be used on the face, neck, and under-eye areas. It offers a gentle, natural rejuvenation that enhances overall skin quality without altering facial contours.
Polynucleotide Prices
At Signature Clinic, we believe in transparent, straightforward pricing. Patients often ask, “How much does Polynucleotide treatment cost in the UK?”
Our Polynucleotide treatments start from £250 per session, depending on the treatment area and number of sessions required. During your consultation, your practitioner will recommend a personalised plan to help you achieve the best results.
| Treatment | Price |
| Polynucleotides – Eyes | £250 per session |
| Polynucleotides – Face | £250 per session |
| Polynucleotides – Hair | £1,700 |
Polynucleotide Treatment In Detail
Benefits of Polynucleotides
- Stimulates collagen and elastin production for firmer skin
- Improves hydration and skin texture
- Reduces fine lines and signs of ageing
- Promotes natural skin regeneration and healing
- Delivers long-lasting, subtle rejuvenation
Polynucleotide Facts and Figures
- Uses highly purified, biocompatible DNA molecules
- Safe for all skin types and ages
- Typically requires 2–3 sessions for best results
- Can be combined with other rejuvenating treatments
- Results improve gradually as collagen renews over time
Polynucleotide Procedure
- Consultation –Your practitioner assesses your skin, goals, and medical history.
- Preparation – A topical numbing cream is applied for comfort.
- Treatment – Polynucleotides are injected into targeted areas using a fine needle.
- Recovery – Mild redness or swelling may appear but usually subsides within 24 hours.
- Results – Skin becomes smoother, firmer, and more radiant over the following weeks.
Meet the Team
Our Surgeons
"The whole experience was excellent, from the initial consultation, the surgery through to the aftercare and the results of the surgery are amazing even better than I was expecting."
"Everything about Signature Clinic was great The staff were welcoming and put you at ease The doctor that done my procedure was amazing I felt very relaxed and confident that I had chosen the perfect place for my procedure I would highly recommend them. Delighted"
"Brilliant service from start to finish, recommended a friend also who equally had the same experience."
have a question?
Polynucleotide FAQ
How many sessions will I need?
Most patients benefit from 2–3 sessions spaced a few weeks apart to achieve optimal results.
When will I see results?
You’ll notice improved skin texture and hydration within a few weeks, with continued improvement as collagen production increases.
Is there any downtime?
Downtime is minimal — most patients can return to normal activities immediately after treatment.
Are polynucleotides safe?
Yes. They are naturally derived, biocompatible, and have been clinically tested for safety and efficacy.
Can I combine this with other treatments?
Absolutely. Polynucleotides can complement microneedling, HIFU, or skin boosters for enhanced rejuvenation.
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